Science
Composition, Compounds, and the Pharmaceutical Hypocrisy
What Urine Actually Is
Contrary to popular misconception, urine is not a toxic waste product. It is filtered blood plasma. The kidneys filter approximately 180 liters of blood per day, removing excess substances the body doesn't need at that moment — not poisons.
Urine is 95% water. The remaining 5% contains a complex mixture of organic and inorganic compounds that varies based on diet, hydration, health status, and metabolic state. Modern analytical chemistry has identified over 3,000 distinct compounds in human urine.
Key Components
Hormones
Urine contains significant amounts of hormones, including:
- Melatonin — Regulates sleep-wake cycles, powerful antioxidant
- DHEA — Precursor to sex hormones, associated with vitality
- Cortisol — Stress response hormone
- Aldosterone — Regulates blood pressure
- Estrogens and Androgens — Sex hormones
- Human Chorionic Gonadotropin (hCG) — Present in pregnancy
Many of these hormones are water-soluble and pass through the kidneys. They remain biologically active and are the basis for several FDA-approved drugs (see below).
Enzymes
- Urokinase — Dissolves blood clots; extracted for pharmaceutical use
- Amylase — Digestive enzyme
- Various proteases — Break down proteins
Immunological Compounds
- Immunoglobulins (antibodies) — IgG, IgA found in urine
- Cytokines — Immune signaling molecules
- Antimicrobial peptides — Natural infection fighters
Urea
Urea comprises about 2% of urine content. Far from being a toxic substance, urea is:
- A natural moisturizer produced by the body
- Used in FDA-approved skincare products (10-50% concentrations)
- Antibacterial and antifungal
- Used medically to treat dry skin, psoriasis, and other conditions
Other Compounds
- Minerals — Sodium, potassium, magnesium, calcium, trace elements
- Vitamins — Water-soluble vitamins (B vitamins, Vitamin C) that exceed body needs
- Amino acids — Building blocks of protein
- Organic acids — Various metabolic byproducts
- Creatinine — Muscle metabolism byproduct
The FDA Hypocrisy
The medical establishment dismisses urine therapy as unscientific quackery. Yet the very same establishment has approved multiple drugs derived from urine:
Premarin
What it is: Conjugated estrogens extracted from pregnant mare urine (the name comes from "PREgnant MARes' urINe").
Status: FDA-approved since 1942. The 283rd most prescribed drug in the United States. Used for hormone replacement therapy.
The irony: Millions of women take horse urine derivatives on their doctor's advice, while the same medical establishment calls human urine consumption dangerous nonsense.
Urokinase
What it is: A thrombolytic enzyme that dissolves blood clots, extracted from human urine.
Status: FDA-approved. Used to treat pulmonary embolism, heart attacks, and blocked catheters.
The irony: Hospitals use purified human urine compounds while telling patients that drinking their own urine is harmful.
Menopur and Fertility Drugs
What they are: Gonadotropins (FSH and LH) extracted from the urine of postmenopausal women.
Status: FDA-approved for fertility treatment. Thousands of dollars per treatment cycle.
The irony: Couples pay thousands for purified urine extracts while free traditional practices are dismissed.
hCG (Human Chorionic Gonadotropin)
What it is: A hormone extracted from the urine of pregnant women.
Status: FDA-approved for various medical uses.
Urea in Skincare
What it is: The same urea found in urine, used in concentrations of 10-50% in therapeutic skincare products.
Status: FDA-approved as a treatment for dry skin, keratosis, and other conditions. Available over-the-counter.
The Pattern Is Clear
The establishment's position is not scientific — it is economic:
- Urine derivatives are acceptable when pharmaceutical companies extract, purify, patent, and sell them at high prices.
- Traditional practice is dismissed when individuals use their own bodies' products for free.
- The same compounds are "medicine" in one context and "dangerous waste" in another.
"Your people are drinking other people's urine but not their own. And it costs dollars, thousands of dollars, while theirs is free and more effective."
— Morarji Desai, Prime Minister of India, on 60 Minutes (1978)
Why No Clinical Trials?
Advocates of conventional medicine often point to the lack of randomized controlled trials on urine therapy. This is presented as evidence of quackery. But the absence of trials reflects institutional priorities, not scientific reality:
- No profit motive: Clinical trials cost tens of millions of dollars. Pharmaceutical companies fund most research because they can recoup costs through patents. You cannot patent urine.
- Institutional bias: The AMA and pharmaceutical industry have no interest in validating free, self-administered therapies that would compete with their products.
- Historical suppression: Traditional practices outside the patent system are systematically ignored or attacked — see the Hoxsey formula, homeopathy, and countless other modalities.
The absence of trials is not evidence of inefficacy. It is evidence of where research money flows — and where it doesn't.
What We Actually Know
Setting aside both uncritical advocacy and knee-jerk dismissal, here is what we can say with confidence:
- Urine is sterile when excreted (in healthy individuals without urinary tract infections).
- Urine contains bioactive compounds — hormones, enzymes, antibodies — that have documented effects.
- Urine-derived compounds are used in medicine.
- External use of urea is FDA-approved at high concentrations.
- The practice has been followed for millennia across multiple cultures.
- Notable practitioners lived long lives — Morarji Desai to 99, for example.
Composition Varies
An important point: urine composition is not static. It reflects:
- Diet: What you eat affects what you excrete
- Hydration: More water = more dilute urine
- Time of day: Morning urine is more concentrated
- Medications: Drugs are excreted through urine
- Health status: Infections, diseases affect composition
This is why traditional texts emphasize diet — the practitioner is literally crafting the medicine they will consume.
Contraindications
We present this information honestly, including when the practice may not be appropriate:
- Active urinary tract infection — Bacteria may be present
- Certain medications — Drugs concentrate in urine
- Kidney disease — Waste filtration may be impaired
- Pregnancy — Caution advised
- Recent chemotherapy — Cytotoxic drugs in urine
As with any significant health practice, discernment is required. We do not recommend anyone begin without thorough research and, where appropriate, consultation with a practitioner familiar with the tradition.
The Bottom Line
Urine is not toxic waste — it is filtered blood plasma containing thousands of biologically active compounds. The medical establishment uses urine derivatives while dismissing traditional practice. The absence of clinical trials reflects economic incentives, not scientific truth.
We present the facts. The decision is yours.